By Lauren A. Beslow. In May 2020, the New England Journal of Medicine reported a series of 5 young adult patients who presented to the same hospital in a two-week period with larger artery strokes as a presenting feature of COVID-19. This high profile NEJM...
Arterial Ischemic Stroke
The International Paediatric Stroke Study (IPSS): A highly successful study vehicle for paediatric stroke research on a global scale
By Nomazulu Dlamini and Alexandra Linds. The International Paediatric Stroke Study (IPSS) was established in 2003 through a visionary collaboration of 11 international colleagues with expertise in paediatric stroke. For over 15 years, the IPSS has served as the...
Teamwork in Pediatric Stroke
By Jenny Wilson and Peter Sporns. Many pediatric hospitals have developed systems to respond to an acute pediatric stroke. These systems involve collaboration between physicians, nurses, and other experts hospital-wide from a diverse set of backgrounds and training,...
Return to school during the COVID pandemic: Information for families with children affected by stroke
By Adam Kirton. As clinicians caring for children with stroke and cerebrovascular disease, most of us have been fielding questions from parents about whether they need to take special precautions to protect their children during the pandemic. There are no clear...
Pediatric Stroke Awareness and Code Stroke Protocols
By Lori Jordan.May is pediatric stroke awareness month. Recognizing a stroke in a child can be difficult. I have been reflecting on how important it is for all healthcare providers and families in our communities to know that strokes occur in children. We recently...
COVID-19 and pediatric stroke—is there a connection?
By Heather Fullerton.One of our earliest pediatric mechanical thrombectomy cases at UCSF Benioff Children’s Hospital was during the 2003 SARS global outbreak. Some of you may remember how children suffered more severe respiratory illnesses with that other...
Vascular effects of Infection in Pediatric Stroke (VIPS)
| Enrolling | Observational | Multi-site | NIH | Heather Fullerton | VIPS II is an international multi-center NIH funded study that proposes to enroll 200 pediatric stroke cases and 200 pediatric stroke-free cases. Biological specimens, imaging, parent interviews and...
Feasibility, Safety and Outcome of Endovascular Recanalization in Childhood Stroke: a worldwide multicenter prospective registry (Save ChildS Pro)
| Enrolling | Prospective Observational Registry |Multi-Site | Peter Sporns | Save ChildS Pro is a prospective registry including all pediatric patients with large vessel occlusion arterial ischemic stroke either treated with endovascular thrombectomy or best medical...
Seizures in Pediatric Stroke (SIPS)
| Closed | Observational | Multi-site | PERF | Christine Fox| SIPS II is an international multi-center PERF funded study that proposed to enroll 300 neonatal and pediatric stroke cases. Imaging, EEGs, medical chart abstraction and epilepsy longitudinal outcome data...
Rehabilitation Early for Congenital Hemiplegia
|Enrolling |Clinical Trial | Multi-Site |Professor Roslyn Boyd | The REACH multisite assessor masked randomized Comparison trial directly compares an equal dose of infant modified Constraint Induced Movement Therapy (Baby CIMT) with infant modified Bimanual upper limb...
Parental Emotional Outcomes in Perinatal Stroke (POPS)
| Enrolling | Observational | Multi-site | Boston Children’s Hospital | Laura Lehman | The POPS study is a prospective multi-site IPSS sub-study that investigates whether an educational video on perinatal stroke etiology will decrease the emotional burden of guilt and...
Examination of PTSD, Anxiety, Depression in parents and children with pediatric arterial ischemic stroke (AIS) and association with stroke outcome (PIPS)
| Enrolling | Observational | Multi-site | Boston Children’s Hospital | Laura Lehman| The PIPS study is a prospective multi-site IPSS sub-study that investigates the association between emotional outcomes (PTSD, anxiety, and depression) and AIS. The study uses...
Advanced Neuroimaging in Pediatric Stroke: Pathophysiology of Injury and Repair in Children with Focal Brain Ischemia
| Enrolling | Observational | Multi-site | Brain Canada | Noma Dlamini | The Brain Canada study is the first multi-center, international, advanced prospective neuroimaging study in childhood stroke. The study focuses on using novel neuroimaging techniques to...
Risk Factors Associated With Stroke in Pediatric Patients Undergoing Fontan
Rehabilitation Early for Congenital Hemiplegia
|Enrolling |Clinical Trial | Multi-Site |Professor Roslyn Boyd | The REACH multisite assessor masked randomized Comparison trial directly compares an equal dose of infant modified Constraint Induced Movement Therapy (Baby CIMT) with infant modified Bimanual upper limb...