Research Studies & Opportunities
Photo Credit: Helen Carlson, Ph.D, Alberta Children’s Hospital
IPSO Members’ Research
Introduction
The International Pediatric Stroke Organization aims to support and promote collaborative research on pediatric cerebrovascular disease. IPSO will serve to facilitate connections amongst investigators with similar research interests. Please fill out the submission form if you would like your collaborative research study listed on the IPSO website.
PASTA (Paediatric Arteriopathy Steroid Aspirin: high dose steroids in children with stroke and unilateral focal arteriopathy) trial. EudraCT 2017-002247-15
|In Development |Clinical Trial |Multi-Site study | Maja Steinlin, Stéphane Chabrier & Manoëlle Kossorotoff | The main goal of PASTA is to determine if a short high dose course of Methylprednisolone/Prednisolone (three intravenous pulses followed by a 4-week oral...
Feasibility, Safety and Outcome of Endovascular Recanalization in Childhood Stroke: a worldwide multicenter prospective registry (Save ChildS Pro)
| Enrolling | Prospective Observational Registry |Multi-Site | Peter Sporns | Save ChildS Pro is a prospective registry including all pediatric patients with large vessel occlusion arterial ischemic stroke either treated with endovascular thrombectomy or best medical...
Seizures in Pediatric Stroke II (SIPS)
| Closed | Observational | Multi-site | PERF | Christine Fox| SIPS II is an international multi-center PERF funded study that proposed to enroll 300 neonatal and pediatric stroke cases. Imaging, EEGs, medical chart abstraction and epilepsy longitudinal outcome data...
Rehabilitation Early for Congenital Hemiplegia
|Enrolling |Clinical Trial | Multi-Site |Professor Roslyn Boyd | The REACH multisite assessor masked randomized Comparison trial directly compares an equal dose of infant modified Constraint Induced Movement Therapy (Baby CIMT) with infant modified Bimanual upper limb...
Parental Emotional Outcomes in Perinatal Stroke (POPS)
| Enrolling | Observational | Multi-site | Boston Children’s Hospital | Laura Lehman | The POPS study is a prospective multi-site IPSS sub-study that investigates whether an educational video on perinatal stroke etiology will decrease the emotional burden of guilt and...
Examination of PTSD, Anxiety, Depression in parents and children with pediatric arterial ischemic stroke (AIS) and association with stroke outcome (PIPS)
| Enrolling | Observational | Multi-site | Boston Children’s Hospital | Laura Lehman| The PIPS study is a prospective multi-site IPSS sub-study that investigates the association between emotional outcomes (PTSD, anxiety, and depression) and AIS. The study uses...
Advanced Neuroimaging in Pediatric Stroke: Pathophysiology of Injury and Repair in Children with Focal Brain Ischemia
| Enrolling | Observational | Multi-site | Brain Canada | Noma Dlamini | The Brain Canada study is the first multi-center, international, advanced prospective neuroimaging study in childhood stroke. The study focuses on using novel neuroimaging techniques to...
Safety and Efficacy of Systemic Anticoagulation Therapy for Treatment of Cerebral Sinus Venous
| Enrolling |Observational |Single Site |Marcela Torres| Keyword(s): Sinus venous thrombosis, anticoagulation, thrombolytic therapy Contact information: Fernando Acosta, Jo Tilley, . Marcela Torres,...
Risk Factors Associated With Stroke in Pediatric Patients Undergoing Fontan
| Enrolling |Observational |Single Site | Jay Duncan | Keyword(s): Arterial ischemic stroke, single ventricle, Fontan, congenital heart disease Contact information: Fernando Acosta, Jo Tilley, . Marcela...
Rehabilitation Early for Congenital Hemiplegia
|Enrolling |Clinical Trial | Multi-Site |Professor Roslyn Boyd | The REACH multisite assessor masked randomized Comparison trial directly compares an equal dose of infant modified Constraint Induced Movement Therapy (Baby CIMT) with infant modified Bimanual upper limb...